Select a product to learn about its potential side effects.
ISENTRESS has a low rate of side effects.
The most common side effects of ISENTRESS include: trouble sleeping, headache, dizziness, nausea, and tiredness. But these are not all possible side effects. Some side effects can be serious.
![ISENTRESS® (raltegravir) Has a Low Rate of Side Effects](https://www.isentress.com/wp-content/uploads/sites/11/2019/10/1070305_Russel_06_0095.jpg)
Some side effects can be serious:
SEVERE SKIN REACTIONS AND ALLERGIC REACTIONS
If you develop a rash with any of the following symptoms, stop using ISENTRESS and call your doctor or get medical help right away:
- Fever
- Generally ill feeling
- Extreme tiredness
- Muscle or joint aches
- Blisters or sores in mouth
- Blisters or peeling of skin
- Redness or swelling of eyes
- Swelling of the mouth, lips, or face
- Problems breathing
Some of these reactions can be serious and may be life-threatening.
LIVER PROBLEMS
Sometimes allergic reactions can affect body organs, such as your liver. Call your doctor right away if you have any of the following signs or symptoms:
- Yellowing of your skin or the whites of your eyes
- Dark or tea-colored urine
- Pale-colored stools (bowel movements)
- Nausea or vomiting
- Loss of appetite
- Pain, aching, or tenderness on the right side of your stomach area
CHANGE IN IMMUNE SYSTEM
Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. You should tell your doctor right away if you start having new symptoms after starting your HIV-1 medicine.
![It is Important to Talk to Your Health Care Team About any Side Effects That You May Be Experiencing After Starting Your HIV-1 Medicine](https://www.isentress.com/wp-content/uploads/sites/11/2019/10/alert-icon.png?w=229)
REMEMBER!
It’s important to talk to your health care team about any side effects that you may be experiencing. They might be able to help.
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ISENTRESS HD has a low rate of side effects.
The most common side effects of ISENTRESS HD include: trouble sleeping, headache, dizziness, nausea, and tiredness. These are not all possible side effects. Some side effects can be serious.
In a 96-week study of adults who were being treated with HIV-1 medicines for the first time, some patients stopped taking the medicine because of side effects.
![ISENTRESS® HD (raltegravir) Has a Low Rate of Side Effects](https://www.isentress.com/wp-content/uploads/sites/11/2019/10/1070305_RAFAEL_15_0125.jpg)
Discontinuation rates were:
1% ISENTRESS HD
2% ISENTRESS
Both ISENTRESS HD and ISENTRESS were taken with Truvada (another HIV-1 medicine).
At 48 weeks, discontinuation rates were 1% (for patients taking ISENTRESS HD + Truvada) and 2% (for patients taking ISENTRESS + Truvada).
Some side effects can be serious:
SEVERE SKIN REACTIONS AND ALLERGIC REACTIONS
If you develop a rash with any of the following symptoms, stop using ISENTRESS and call your doctor or get medical help right away:
- Fever
- Generally ill feeling
- Extreme tiredness
- Muscle or joint aches
- Blisters or sores in mouth
- Blisters or peeling of skin
- Redness or swelling of eyes
- Swelling of the mouth, lips, or face
- Problems breathing
Some of these reactions can be serious and may be life-threatening.
LIVER PROBLEMS
Sometimes allergic reactions can affect body organs, such as your liver. Call your doctor right away if you have any of the following signs or symptoms:
- Yellowing of your skin or the whites of your eyes
- Dark or tea-colored urine
- Pale-colored stools (bowel movements)
- Nausea or vomiting
- Loss of appetite
- Pain, aching, or tenderness on the right side of your stomach area
CHANGE IN IMMUNE SYSTEM
Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. You should tell your doctor right away if you start having new symptoms after starting your HIV-1 medicine.
![It is Important to Talk to Your Health Care Team About any Side Effects That You May Be Experiencing After Starting Your HIV-1 Medicine](https://www.isentress.com/wp-content/uploads/sites/11/2019/10/alert-icon.png?w=229)
REMEMBER!
It’s important to talk to your health care team about any side effects that you may be experiencing. They might be able to help.